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Antidepressant Selection Tool
How-to Guide

Step-by-step instructions for using the Antidepressant Selection Tool

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1. Select Patient's Health Conditions
  • Click the checkbox to the left of the health condition to select it
  • Health conditions are listed in alphabetical order
2. Select Patient's Medications
  • Medications are grouped by their general use
    • e.g. NSAIDs are in the pain group
  • Click the box to show medications within the group
  • Click the checkbox to the left of the medication to select it
  • NOTE: If you cannot find a medication in the list, it is unlikely to have clinically significant interactions with the antidepressants included in the selction tool
3. Submit Patient's Health Conditions and Medications
  • Click the "Submit" button
4. Click Antidepressants to Review Alerts
  • Interpreting Alerts
    • Color and Symbol Explanation
    • Benefit Identified
      Benefits may outweigh risks
      ⚠️ Concern Identified
      Risks may outweight benefits
      Contraindicated
    • Disease State Interactions ⚕️
      • Explanation of how patient's health conditions and antidepressants may interact
    • Drug Interactions 💊
      • Explanation of how patient's medications and antidepressants may interact
    • Antidepressant Dosing Information
      • Click indication to display dosing information
6. Filter Antidepressants
  • By Antidepressant Drug Class
    • Click the dropdown box to the right of "Drug Class"
    • Select the drug class of antidepressants you want to see:
      • All Antidepressants (regardless of drug class)
      • Selective Serotonin Reuptake Inhibitors (SSRIs)
      • Selective Norepinephrine Reuptake Inhibitors (SNRIs)
      • Atypical Antidepressants
  • By Alerts
    • Click the dropdown box to the right of "Alerts"
    • Select the alerts you want to see:
      • All Alerts
      • Benefits Only: Only show antidepressants with benefits
      • Warnings Only: Only show antidepressants with warnings
      • No Warnings: Show antidepressants without warnings (may or may not have benefits)
7. Miscellaneous
  • Send to Switching Tool
    • Provides information on how to switch to selected antidepressant
    • Redirects to the Antidepressant Switching Tool with the selected antidepressant loaded as the new antidepressant
  • Legend
    • Displays color and symbol explanation for antidepressants
  • Reports Bugs
    • Send a report if the Antidepressant Selection Tool is not working as expected
  • Give Feedback
    • Feel free to share your thoughts, suggestions, or questions to help us improve the Antidepressant Selection Tool

Frequently Asked Questions

Initially, yes. The Antidepressant Selection Tool currently focuses on antidepressants, helping you find the safest and most effective options for your patients based on their health conditions and current medications. We plan to expand the tool to include other psychiatric medications over time, based on user feedback.

Yes, for now. The Antidepressant Selection Tool currently focuses on drug interactions with clinically significant implications, like contraindications and the need for dose adjustments. We plan to expand the tool to assess other relevant drug interactions in the future.

Currently, the tool is designed for adult patients. We may consider adding functionality for other populations, such as pediatric or pregnant patients, as we gather more feedback and refine the tool.

The Antidepressant Selection Tool is based on clinical studies and package insert information, but it’s intended to support—not replace—your clinical judgment. It highlights key risks and benefits based on common interactions and clinical evidence.